gene 527 words KG: CD163 2026-03-17
kind:genesection:genesstate:published
Contents

CD163 (Hemoglobin Scavenger Receptor)

🧬 Gene Info
Gene SymbolCD163
Full NameCD163 Molecule (Hemoglobin Scavenger Receptor)
AliasesHemoglobin Scavenger Receptor
Chromosome12p13.31
Protein TypeReceptor
FunctionCD163 (Cluster of Differentiation 163), also known as the Hemoglobin Scavenger Receptor, is a member of the scavenger receptor family.
PathwaysTGF-β
UniProt ID[Q86VB7](https://www.uniprot.org/uniprot/Q86VB7)
Ensembl IDENSG00000177575
GeneCardsCD163
Human Protein AtlasCD163
Extracellular domain9 scavenger receptor cysteine-rich (SRCR) domains
Transmembrane regionSingle pass
Cytoplasmic tailSignaling capabilities
Associated DiseasesALS, Aging, Cancer, Inflammation, Ms, Neuroinflammation
InteractionsCD68, CX3CR1, CD36, NRF2, TNF, NEAT1
KG Connections322 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Knowledge Graph (12 edges)

CD163 phosphorylates CD36
CD163 phosphorylates CD68
CD163 phosphorylates NRF2
CD163 phosphorylates TNF
CD163 phosphorylates NEUROINFLAMMATION
CD163 biomarker_for MMP9
CD163 associated_with CD14
CD163 associated_with CD68
CD163 biomarker_for MMP2
CD163 activates CD68