| Gene Symbol | HSP90B1 |
| Chromosome | 15q26.3 |
| Function | GRP94 (encoded by HSP90B1) is a member of the heat shock protein 90 family, distinguished by its ER-resident localization and unique client protein repertoire |
| Molecular Weight | 90 kDa |
| Pathways | Mapk |
| UniProt ID | P14625 |
| NCBI Gene ID | 27197 |
| OMIM | 611719 |
| GeneCards | HSP90B1 |
| Human Protein Atlas | HSP90B1 |
| Sensor Function | Acts as ER stress sensor |
| Chaperone Induction | Upregulated during ER stress |
| XBP1 Splicing | Facilitates XBP1 processing |
| ATF6 Activation | Interacts with ATF6 pathway |
| Associated Diseases | neurodegeneration |
| Interactions | CDK1, EGFR, ERBB2, FOXO1, GENES, GNB4 |
| KG Connections | 37 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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