| Gene Symbol | NRCAM |
| Protein Type | Gene |
| Function | is a member of the L1 family of cell adhesion molecules (L1-CAMs). |
| Primary Expression | the developing brain and continues to be expressed in adult neurons |
| Pathways | Epithelial-Mesenchymal Transition |
| Ensembl ID | ENSG00000163631 |
| GeneCards | NRCAM |
| Human Protein Atlas | NRCAM |
| Neuronal Migration | During cortical development, NRCAM guides neuronal precursors to their proper positions |
| Axon Guidance | Functions as a guidance molecule for developing axons, particularly in the optic chiasm and corticospinal tract |
| Synapse Formation | Localizes to synaptic membranes and participates in synapse assembly and function |
| Node of Ranvier Formation | Clusters at nodes of Ranvier in myelinated axons alongside other L1-CAMs (L1, Nr-CAM) |
| Autism Spectrum Disorder (ASD) | Multiple studies have identified NRCAM variants in individuals with autism |
| Multiple Sclerosis (MS) | Gene associations reported in GWAS studies |
| Epilepsy | Rare variants may contribute to seizure susceptibility |
| Associated Diseases | Cancer, Carcinoma, Hepatocellular Carcinoma, Liver Cancer |
| Interactions | MACF1 |
| KG Connections | 101 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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