Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about OPRL1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | OPRL1 |
| Key Genes/Proteins | GBM, GENES, HCRTR1, MAPK, RNA, AND |
| Related Diseases | Cancer, ALS, Glioblastoma, Als |
Knowledge base pages for this entity
graph TD
OPRL1["OPRL1"]
OPRL1 -->|"expressed in"| Cancer["Cancer"]
OPRL1 -->|"expressed in"| ALS["ALS"]
OPRL1 -->|"expressed in"| Glioblastoma["Glioblastoma"]
OPRL1 -.biomarker for.-> Als["Als"]
OPRL1 -->|"expressed in"| GBM["GBM"]
OPRL1 -->|"expressed in"| HCRTR1["HCRTR1"]
Curcumin["Curcumin"] -->|"downregulates"| OPRL1
CPLX3["CPLX3"] -.biomarker for.-> OPRL1| Target | Relation | Type | Str |
|---|---|---|---|
| Cancer | expressed_in | disease | 0.65 |
| ALS | expressed_in | disease | 0.65 |
| Glioblastoma | expressed_in | disease | 0.65 |
| Als | biomarker_for | disease | 0.65 |
| Cancer | biomarker_for | disease | 0.65 |
| Glioblastoma | biomarker_for | disease | 0.65 |
| GBM | expressed_in | gene | 0.60 |
| GENES | associated_with | gene | 0.60 |
| HCRTR1 | expressed_in | gene | 0.60 |
| MAPK | expressed_in | gene | 0.60 |
| RNA | expressed_in | gene | 0.60 |
| AND | associated_with | gene | 0.60 |
| LRRTM2 | associated_with | gene | 0.60 |
| CPLX3 | expressed_in | gene | 0.60 |
| GLIOBLASTOMA | expressed_in | gene | 0.60 |
| CANCER | expressed_in | gene | 0.60 |
| Mapk | expressed_in | pathway | 0.60 |
| GBM | biomarker_for | gene | 0.60 |
| MAPK | biomarker_for | gene | 0.60 |
| HCRTR1 | biomarker_for | gene | 0.60 |
| GLIOBLASTOMA | biomarker_for | gene | 0.60 |
| Mapk | biomarker_for | pathway | 0.60 |
| Igf | expressed_in | protein | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||