| Gene Symbol | DR5 |
| Chromosome | 4p16.1 |
| Protein Type | Receptor |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | </th><td>Plasma membrane, dendritic spines</td></tr> |
| Molecular Weight | 52.9 kDa |
| Amino Acids | 477 aa |
| Pathways | Akt, Apoptosis, Cell Cycle, Pi3K |
| UniProt ID | P21918 |
| NCBI Gene ID | 1816 |
| Ensembl ID | ENSG00000169679 |
| GeneCards | DR5 |
| Human Protein Atlas | DR5 |
| Extracellular N-terminus | Contains glycosylation sites and contributes to ligand binding |
| Intracellular C-terminus | Contains phosphorylation sites for receptor regulation |
| Associated Diseases | ALS |
| Interactions | AKT, AND, APOPTOSIS, BAD, BCL-2, CANCER |
| KG Connections | 103 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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