protein 1,169 words KG: ERN1PROTEIN
Contents

ERN1/IRE1 Protein — ER Stress Sensor

🔬 Protein Info
Gene SymbolERN1PROTEIN
Chromosome6p21.1.
Functionis a critical transmembrane protein that functions as a primary sensor of endoplasmic reticulum (ER) stress.
GeneCardsERN1PROTEIN
Human Protein AtlasERN1PROTEIN
Kinase DomainCatalyzes autophosphorylation upon activation
RNase DomainCleaves XBP1 mRNA to produce the spliced form (XBP1s)
Associated DiseasesAD, Aging, ALI, Als, Alzheimer
Known Drugs/Compoundsrapamycin
InteractionsABCD3, ACETYL-COA, Actin, AKT, AKT1, AKT1S1
KG Connections980 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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