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protein 653 words KG: MTORC1PROTEIN
Contents

mTORC1 Protein — Mechanistic Target of Rapamycin Complex 1

🔬 Protein Info
Gene SymbolMTORC1
AliasesMTORC1PROTEIN
Associated DiseasesAD, ADH, Ageing, Aging, Als, AMI
Known Drugs/CompoundsAmino Acids, Arginine, Lysosomal Cholesterol, MHY1485, Pterostilbene, rapamycin
InteractionsABCA1, ACETYL-COA, ACLY, ACOX1, ACTB, Actin
KG Connections1907 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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UniProtWikipedia

Related Hypotheses (11)

APOE-Dependent Autophagy Restoration
Score: 0.89AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.83Transcriptional Autophagy-Lysosome Coupling
Score: 0.78Circadian-Synchronized Proteostasis Enhancement
Score: 0.74The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.65Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62TFEB-PGC1α Mitochondrial-Lysosomal Decoupling
Score: 0.62Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62TREM2-mediated microglial tau clearance enhancement
Score: 0.62HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57

Related Analyses (10)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archivedMitochondrial transfer between astrocytes and neurons
neurodegeneration · archivedTau propagation mechanisms and therapeutic interception poin
neurodegeneration · archivedLipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completedRNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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