protein 1,133 words KG: VEGFPROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

Vascular Endothelial Growth Factor (VEGF)

🔬 Protein Info
Gene SymbolVEGF
AliasesVascular Endothelial Growth Factor
FunctionVEGF serves multiple physiological functions
Primary Expressionhippocampus, motor cortex, cerebellum, cortex, striatum
PathwaysAkt, Amyloid, Apoptosis, Complement, Epigenetic
UniProt ID[P15692](https://www.uniprot.org/uniprot/P15692)
NCBI Gene ID7422
GeneCardsVEGF
Human Protein AtlasVEGF
StrategyAgent
Gene therapyCERE-110 (AAV-VEGF)
PeptideVEGF165b isoforms
Receptor agonistVEGF-A variants
Small moleculeVarious compounds
Associated DiseasesALS, Aging, Alzheimer, Alzheimer'S Disease
Known Drugs/CompoundsRAPAMYCIN, bevacizumab, levodopa, LEVODOPA, QUERCETIN, rapamycin
InteractionsFGF2, ANGPT1, PDGFRB, VEGFB, BMP2, STAT3
KG Connections1347 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (11)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.48
Hypocretin-Neurogenesis Coupling Therapy
Score: 0.45
Vascular mural cell degeneration precedes and exacerbates pa
Score: 0.52
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68

Related Analyses (11)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived

Related Experiments (2)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40
Neural Stem Cell Therapy for Alzheimer's Disease
clinical · proposed · Score: 0.40

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Wnt/β-Catenin Signaling Pathway in Neurodegeneration
mechanism · Pages share 3 hypotheses
WNK1-Bilirubin Signaling in Neuroinflammation and Neuro
mechanism · Pages share 3 hypotheses
vip-vasoactive-intestinal-peptide-signaling-neurodegene
mechanism · Pages share 3 hypotheses
VEGF Signaling and Cerebral Angiogenesis in Neurodegene
mechanism · Pages share 3 hypotheses