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Mechanism: psilocybin-neuropsychiatric-ad
mechanism
562 words
KG: AD
Contents
psilocybin-neuropsychiatric-ad
⚙
Mechanism Info
Name
AD
Key Genes/Proteins
A2M
,
ABCA1
,
ABCB1
,
ABCD3
,
ABCG1
,
ACTB
Related Diseases
AGE
Linked Hypotheses
47 hypotheses
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Knowledge Graph
Related Hypotheses (30)
Closed-loop focused ultrasound targeting EC-II SST interneur
Score: 1.00
Closed-loop tACS targeting EC-II SST interneurons to block t
Score: 1.00
Closed-loop tACS targeting EC-II PV interneurons to suppress
Score: 0.99
Closed-loop tACS targeting EC-II parvalbumin interneurons to
Score: 0.98
Closed-loop optogenetic targeting PV interneurons to restore
Score: 0.94
Plasma p-tau217-Triggered Exosome Dosing Maximizes lncRNA-00
Score: 0.94
Closed-loop focused ultrasound targeting CA1 PV interneurons
Score: 0.93
Metabolic NAD+ Salvage Pathway Enhancement Through NAMPT Ove
Score: 0.89
Closed-loop tACS targeting EC-II PV interneurons to enhance
Score: 0.87
Closed-loop focused ultrasound targeting EC-II PV interneuro
Score: 0.86
Real-time gamma-guided transcranial focused ultrasound targe
Score: 0.83
Neutrophil Extracellular Trap (NET) Inhibition
Score: 0.81
CSF sTREM2 as Pharmacodynamic Biomarker for Therapeutic Wind
Score: 0.80
NMN Supplementation Restores SIRT1/p66Shc/FOXO3 Epigenetic A
Score: 0.79
ALOX15-Driven Enzymatic Ferroptosis in AD Oligodendrocytes v
Score: 0.78
H3: SIRT1 Insufficiency Disconnects Metabolic Sensing from E
Score: 0.77
Senescence-Activated NAD+ Depletion Rescue
Score: 0.76
Metabolic Inflexibility Precedes Transcriptional Reprogrammi
Score: 0.73
Adenosine-Astrocyte Metabolic Reset
Score: 0.73
Soluble TREM2 (sTREM2) as Therapeutic Mimic — Decoupling Pha
Score: 0.71
Noradrenergic-Tau Propagation Blockade
Score: 0.71
Selective LXRβ agonists restore ABCA1/ABCG1 expression and A
Score: 0.71
NAD+ Decline and SIRT1 Deficiency Drive Epigenetic Reprogram
Score: 0.70
SARM1-Mediated NAD+ Depletion as Terminal Executor of MCT1-D
Score: 0.70
Pharmacological EZH2 Inhibition Resets Polycomb-Mediated Rep
Score: 0.68
CSF Soluble TREM2 Fragment Ratio as Priming State Indicator
Score: 0.68
TFEB-mediated transcriptional upregulation of lysosomal gene
Score: 0.68
SIRT6-NAD+ Axis Enhancement Therapy
Score: 0.67
Stathmin-2 Splice Switching to Prevent Axonal Degeneration A
Score: 0.66
Conserved 5' Terminal Stem-Loop in NORAD Enables ASO-Mediate
Score: 0.65
Show 25 more
Knowledge Graph (12 edges)
GSS
implicated_in
AD
CYP2E1
implicated_in
AD
IDH2
implicated_in
AD
IDH1
implicated_in
AD
VEGFA
implicated_in
AD
EEF1A1
implicated_in
AD
APOB
implicated_in
AD
MET
implicated_in
AD
MCL1
implicated_in
AD
SF3B1
implicated_in
AD
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