concept

SERPINE2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SERPINE2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

23Connections

0Hypotheses

0Analyses

19Outgoing

4Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	SERPINE2
Key Genes/Proteins	RNA, AND, CD39, DEMENTIA, OLIGODENDROCYTE, LRP1
Related Diseases	Ischemia, Dementia, ALS, Vascular Dementia, Als

Wiki Pages (2)

Knowledge base pages for this entity

TERT Gene

gene · 2193 words

→

PLG — Plasminogen

gene · 2063 words

→

Pathway Diagram

graph TD
    SERPINE2["SERPINE2"]
    SERPINE2 -->|"interacts"| LRP1["LRP1"]
    SERPINE2 -->|"regulates"| Oligodendrocyte_Progenitor_Cel["Oligodendrocyte Progenitor Cell Differentiation"]
    SERPINE2 -->|"interacts"| Ischemia["Ischemia"]
    SERPINE2 -->|"interacts"| Dementia["Dementia"]
    SERPINE2 -->|"activates"| ALS["ALS"]
    SERPINE2 -->|"interacts"| Vascular_Dementia["Vascular Dementia"]
    SERPINE2 -->|"activates"| Als["Als"]
    SERPINE2 -->|"interacts"| RNA["RNA"]
    DEMENTIA["DEMENTIA"] -->|"interacts"| SERPINE2
    OLIGODENDROCYTE["OLIGODENDROCYTE"] -->|"activates"| SERPINE2
    RNA -->|"interacts"| SERPINE2

Outgoing (19)

Target	Relation	Type	Str
senescent cells	expressed_in	cell_type	0.90
Oligodendrocyte Progenitor Cell Differentiation	regulates	process	0.85
Ischemia	interacts_with	disease	0.65
Dementia	interacts_with	disease	0.65
ALS	activates	disease	0.65
Vascular Dementia	interacts_with	disease	0.65
Als	activates	disease	0.65
RNA	interacts_with	gene	0.60
AND	activates	gene	0.60
CD39	associated_with	gene	0.60
DEMENTIA	interacts_with	gene	0.60
Oligodendrocyte	activates	cell_type	0.60
OLIGODENDROCYTE	activates	gene	0.60
LRP1	associated_with	gene	0.60
Opc	activates	cell_type	0.60
App	interacts_with	protein	0.60
White Matter	expressed_in	brain_region	0.55
Progenitor Cell	expressed_in	cell_type	0.55
Oligodendrocyte	expressed_in	cell_type	0.55

Incoming (4)

Source	Relation	Type	Str
DEMENTIA	interacts_with	gene	0.60
OLIGODENDROCYTE	activates	gene	0.60
LRP1	associated_with	gene	0.60
RNA	interacts_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found