gene 740 words KG: TLR1
Contents

TLR1 Gene

🧬 Gene Info
Gene SymbolTLR1
Full NameToll-Like Receptor 1
Chromosome4p14
Protein TypeReceptor
Primary Expressionmicroglia and contributes to neuroinflammatory processes in neurodegenerative diseases
Molecular Weight90 kDa
Amino Acids799 aa
PathwaysNF-κB, MAPK, MAPK pathway
UniProt IDQ9Y5S2
NCBI Gene ID7099
Ensembl IDENSG00000174125
OMIM601194
GeneCardsTLR1
Human Protein AtlasTLR1
Pattern recognition receptorDetects microbial-associated molecular patterns (MAMPs)
Associated Diseasesneurodegeneration
InteractionsCMPK2, CYTOKINES, ECSIT, IBA1, IL6, INFLAMMATION
KG Connections48 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

Cross-Seeding: Gut Microbiome-Derived Bacterial Curli and Fu
Score: 0.54

Knowledge Graph (12 edges)

TLR4 expressed_in TLR1
IL1B expressed_in TLR1
TLR3 expressed_in TLR1
RAGE expressed_in TLR1
IRAK2 expressed_in TLR1
IL10 expressed_in TLR1
IRAK1 expressed_in TLR1
IKBKG expressed_in TLR1
TLR2 expressed_in TLR1
TLR1 expressed_in HMGB1

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