gene 607 words KG: TLR3
Contents

TLR3 — Toll-Like Receptor 3

🧬 Gene Info
Gene SymbolTLR3
Full NameToll-Like Receptor 3
Chromosome4q35
Protein TypeReceptor
FunctionTLR3 is expressed in microglia, astrocytes, neurons, and oligodendrocytes.
Primary Expressionvarious cell types in the brain and plays a critical role in antiviral immune responses and has been implicated in neurodegenerative diseases
Amino Acids904 aa
PathwaysNF-κB, MAPK pathway
UniProt IDQ9Y5Y9
NCBI Gene ID7098
Ensembl IDENSG00000164342
OMIM603029
GeneCardsTLR3
Human Protein AtlasTLR3
Viral dsRNA sensorRecognizes dsRNA from viral infections
Associated DiseasesMs
InteractionsADAR1, AGING, AND, APOPTOSIS, CANCER, CGAS
KG Connections170 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Knowledge Graph (12 edges)

TRIF participates_in TLR3
TLR3 regulates CXCL10
MYD88 expressed_in TLR3
TLR3 expressed_in DISC1
TLR4 expressed_in TLR3
IL1B expressed_in TLR3
TLR3 expressed_in RAGE
TLR3 expressed_in IRAK2
TLR3 expressed_in IL10
TLR3 expressed_in IRAK1

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