| Gene Symbol | TRPM2 |
| Full Name | Transient Receptor Potential Cation Channel Subfamily M Member 2 |
| Aliases | Page for TRPM2, Page for TRPM2 Protein, Transient Receptor Potential Melastatin 2 |
| Chromosome | 21q22.12 |
| Protein Type | Channel |
| Function | is a calcium-permeable cation channel activated by oxidative stress and ADP-ribose. |
| Molecular Weight | 203 kDa |
| Amino Acids | 1705 aa |
| Pathways | Oxidative Stress |
| UniProt ID | TRPM2 |
| Ensembl ID | ENSG00000086848 |
| GeneCards | TRPM2 |
| Human Protein Atlas | TRPM2 |
| N-terminal MHR domains | Four melastatin homology regions mediate tetramerization |
| Transmembrane domain | Six transmembrane helices (S1-S6) forming the pore |
| Associated Diseases | Als, Bipolar, Bipolar Disorder, BIPOLAR_DISORDER, Depression |
| Interactions | AMPK, AND, APOPTOSIS, ATG5, BECN1, CAMK2 |
| KG Connections | 135 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!