Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CAMK2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Hepatic Mitochondrial Oxidation | regulates | process | 0.90 |
| Intrahepatic Lipolysis | regulates | process | 0.90 |
| Gluconeogenesis | regulates | process | 0.90 |
| Neural Repair | regulates | process | 0.85 |
| Neuroregeneration | involved_in | process | 0.85 |
| CREB | phosphorylates | gene | 0.85 |
| LC3 | activates | gene | 0.70 |
| oxidative stress response | participates_in | pathway | 0.70 |
| autophagy pathway | participates_in | pathway | 0.70 |
| LC3 | inhibits | gene | 0.60 |
| CASP3 | activates | gene | 0.60 |
| DMPK | activates | gene | 0.60 |
| GFAP | activates | gene | 0.60 |
| HIF1A | activates | gene | 0.60 |
| HMGCR | activates | gene | 0.60 |
| LAMP1 | activates | gene | 0.60 |
| MAP1LC3B | activates | gene | 0.60 |
| PIK3C3 | activates | gene | 0.60 |
| PLP1 | activates | gene | 0.60 |
| PRKDC | activates | gene | 0.60 |
| SLC17A6 | activates | gene | 0.60 |
| SQSTM1 | activates | gene | 0.60 |
| TRPM2 | activates | gene | 0.60 |
| ULK1 | activates | gene | 0.60 |
| apoptosis pathway | participates_in | pathway | 0.60 |
| DMSO | activates | gene | 0.60 |
| DNA | activates | gene | 0.60 |
| GFP | activates | gene | 0.60 |
| HIF | activates | gene | 0.60 |
| LC3B | activates | gene | 0.60 |
| ROS | activates | gene | 0.60 |
| VPS34 | activates | gene | 0.60 |
| traumatic brain injury | activates | disease | 0.60 |
| blood-brain barrier | participates_in | pathway | 0.60 |
| endothelial cells | expressed_in | cell_type | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Cytosolic Calcium | activates | compound | 0.95 |
| Millimeter waves | upregulates | compound | 0.85 |
| BECN1 | activates | gene | 0.70 |
| ANXA1 | activates | gene | 0.60 |
| ANXA1 | inhibits | gene | 0.60 |
| BECN1 | inhibits | gene | 0.60 |
| ATG5 | activates | gene | 0.60 |
| AMPK | activates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||