gene 898 words KG: USP7
Contents

USP7 Gene

🧬 Gene Info
Gene SymbolUSP7
Full NameUbiquitin-Specific Peptidase 7
AliasesHAUSP Deubiquitinase
Chromosome16p13.2
Protein TypeEnzyme
Functionencodes a deubiquitinating enzyme (DUB) that removes ubiquitin from target proteins, regulating their stability and function.
Molecular Weight128 kDa
Amino Acids102 aa
PathwaysNF-κB, Wnt signaling
UniProt IDQ93009
NCBI Gene ID7874
Ensembl IDENSG00000187555
OMIM602519
GeneCardsUSP7
Human Protein AtlasUSP7
Associated DiseasesAls, Cancer, glioblastoma, Huntington's disease
Known Drugs/CompoundsH2O2
InteractionsALOX15, AMBRA1, AND, AR, ATM, CANCER
KG Connections157 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

USP7 inhibits PROTEIN_DEGRADATION
USP7 inhibits HNRNPA1
USP7 inhibits ALOX15
MLKL regulates USP7
USP7 modifies AMBRA1
H2O2 activates USP7
HNRNPA1 inhibits USP7
ALOX15 inhibits USP7
YY1 interacts_with USP7
USP7 activates AMBRA1

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