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C9orf72 — Chromosome 9 Open Reading Frame 72

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-genes-c9orf72
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C9ORF72
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sluggenes-c9orf72
entity_typegene
kg_node_idC9ORF72
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Linked Artifacts (230)
mentions🧫s:** - Single-cell RNA-seq to measure editing efficiency acr70%
related🧫s:** - Single-cell RNA-seq to measure editing efficiency acr63%
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see_also📖SRRM2 — Serine/Arginine Repetitive Matrix 260%
see_also📖trim260%
see_also📖Actin Cytoskeleton Dynamics in Neurodegeneration60%
see_also📖Aging vs Neurodegeneration: Mechanistic Comparison Matrix60%
see_also📖C9orf72 Dipeptide Repeat Proteins60%
see_also📖HEXA (Redirect)60%
see_also📖RALB Gene - RAS-Related Protein Ral-B60%
see_also📖stathmin60%
see_also📖WDFY3 Gene60%
see_also📖DDX3X Gene60%
see_also📖KCNJ2 — Kir2.1 Inward Rectifier Potassium Channel60%
see_also📖RAB8A — RAB8A, Member RAS Oncogene Family60%
see_also📖Lysosomal Dysfunction in Neurodegeneration60%
see_also📖ACTB Gene60%
see_also📖atg10160%
see_also📖RAB1A — Ras-Related Protein Rab-1A60%
see_also📖RAB39B Gene60%
see_also📖WDR41 Gene60%
see_also📖Calcium Signaling Dysregulation in Alzheimer's Disease60%
see_also📖Proteostasis Therapeutics60%
see_also📖MARK2 Gene60%
see_also📖STAU2 Gene60%
mentions🧪Mitochondrial-Lysosomal Contact Site Engineering50%
mentions🧪Arginine Methylation Enhancement Therapy50%
mentions🧪Cryptic Exon Silencing Restoration50%
mentions🧪Synaptic Phosphatidylserine Masking via Annexin A1 Mimetics50%
mentions🧪Heat Shock Protein 70 Disaggregase Amplification50%
mentions🧪Autophagosome Maturation Checkpoint Control50%
mentions🧪PARP1 Inhibition Therapy50%
mentions🧪Low Complexity Domain Cross-Linking Inhibition50%
mentions🧪Glycine-Rich Domain Competitive Inhibition50%
mentions🧪Axonal RNA Transport Reconstitution50%
mentions🧪Circadian-Gated Maresin Biosynthesis Amplification50%
mentions🧪Lysosomal Membrane Repair Enhancement50%
mentions🧪Stress Granule Phase Separation Modulators50%
mentions🧪Senescence-Associated Myelin Lipid Remodeling50%
mentions🧪R-Loop Resolution Enhancement Therapy50%
mentions🧪Serine/Arginine-Rich Protein Kinase Modulation50%
mentions🧪Vocal Cord Neuroplasticity Stimulation50%
mentions🧪Nucleolar Stress Response Normalization50%
mentions🧪Cross-Seeding Prevention Strategy50%
mentions🧫s:** - Single-cell RNA-seq to measure editing efficiency acr50%
mentions🧪Mitochondrial-Lysosomal Contact Site Engineering50%
mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer50%
mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones50%
mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction50%
mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy50%
mentions🧪Competitive APOE4 Domain Stabilization Peptides50%
mentions🧪APOE Isoform Expression Across Glial Subtypes50%
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mentions🧪GFAP-Positive Reactive Astrocyte Subtype Delineation50%
mentions🧪LRP1-Dependent Tau Uptake Disruption50%
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mentions🧪TREM2-mediated microglial tau clearance enhancement50%
mentions🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia50%
mentions🧪VCP-Mediated Autophagy Enhancement50%
mentions🧪Trinucleotide Repeat Sequestration via CRISPR-Guided RNA Tar50%
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related🔬What are the mechanisms underlying rna binding protein dysre50%
related🔬What are the mechanisms underlying synaptic pruning by micro50%
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mentions🧫Mechanism: C9orf72 Hexanucleotide Repeat Expansion in ALS/FT40%
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mentions📖Technical University of Munich (TUM)40%
mentions📖University College London (UCL)40%
mentions📖University College London40%
mentions📖University of British Columbia40%
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mentions📖University of California, Irvine (UCI)40%
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mentions📖University of Colorado Anschutz Medical Campus40%
mentions📖University of Edinburgh40%
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mentions📖University of Lille40%
mentions📖University of Miami40%
mentions📖University of Miami40%
mentions📖University of Michigan40%
mentions📖University of Minnesota40%
mentions📖University of North Carolina (UNC)40%
mentions📖University of North Carolina at Chapel Hill40%
mentions📖University of Oxford40%
mentions📖University of Oxford40%
mentions📖University of Pennsylvania (UPenn)40%
mentions📖University of Rostock40%
mentions📖University of Sheffield40%
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mentions📖University of Texas Southwestern Medical Center40%
mentions📖University of Tokyo40%
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related🧪Multi-Modal Stress Response Harmonization40%
related🧪Retinal Vascular Microcirculation Rescue40%
related🧪Cryptic Exon Silencing Restoration40%
related🧪Heat Shock Protein 70 Disaggregase Amplification40%
related🧪Autophagosome Maturation Checkpoint Control40%
related🧪PARP1 Inhibition Therapy40%
related🧪Low Complexity Domain Cross-Linking Inhibition40%
related🧪Ocular Immune Privilege Extension40%
related🧪Glycine-Rich Domain Competitive Inhibition40%
related🧪Axonal RNA Transport Reconstitution40%
related🧪Lysosomal Membrane Repair Enhancement40%
related🧪Lysosomal Calcium Channel Modulation Therapy40%
related🧪Stress Granule Phase Separation Modulators40%
related🧪Transcriptional Autophagy-Lysosome Coupling40%
related🧪Digital Twin-Guided Metabolic Reprogramming40%
related🧪Lysosomal Positioning Dynamics Modulation40%
related🧪Lysosomal Enzyme Trafficking Correction40%
related🧪R-Loop Resolution Enhancement Therapy40%
related🧪Serine/Arginine-Rich Protein Kinase Modulation40%
related🧪Vocal Cord Neuroplasticity Stimulation40%
related🧪Nucleolar Stress Response Normalization40%
related🧪Cross-Seeding Prevention Strategy40%
related🧪RNA Granule Nucleation Site Modulation40%
related🧪Mitochondrial-Lysosomal Contact Site Engineering40%
related🧪Arginine Methylation Enhancement Therapy40%
related🧪Cryptic Exon Silencing Restoration40%
related🧪Synaptic Phosphatidylserine Masking via Annexin A1 Mimetics40%
related🧪Heat Shock Protein 70 Disaggregase Amplification40%
related🧪Autophagosome Maturation Checkpoint Control40%
related🧪PARP1 Inhibition Therapy40%
related🧪Low Complexity Domain Cross-Linking Inhibition40%
related🧪Glycine-Rich Domain Competitive Inhibition40%
related🧪Axonal RNA Transport Reconstitution40%
related🧪Circadian-Gated Maresin Biosynthesis Amplification40%
related🧪Lysosomal Membrane Repair Enhancement40%
related🧪Stress Granule Phase Separation Modulators40%
related🧪Senescence-Associated Myelin Lipid Remodeling40%
related🧪R-Loop Resolution Enhancement Therapy40%
related🧪Serine/Arginine-Rich Protein Kinase Modulation40%
related🧪Vocal Cord Neuroplasticity Stimulation40%
related🧪Nucleolar Stress Response Normalization40%
related🧪Cross-Seeding Prevention Strategy40%
related🔬What are the mechanisms underlying rna binding protein dysre40%
related🔬RNA binding protein dysregulation across ALS FTD and AD40%
related🔬What are the mechanisms underlying tdp-43 phase separation t40%
related🔬TDP-43 undergoes liquid-liquid phase separation that becomes40%
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related🔬Can speech, gait, retinal imaging, sleep, and smartphone dat40%
related🔬What are the mechanisms underlying autophagy-lysosome pathwa40%
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mentions🔬What are the mechanisms underlying tdp-43 phase separation t35%
mentions🔬What are the mechanisms underlying autophagy-lysosome pathwa35%
mentions🔬What are the mechanisms underlying digital biomarkers and ai35%
mentions🔬What are the mechanisms underlying senolytic therapy for age35%
mentions🔬What are the mechanisms underlying neuroinflammation resolut35%
mentions🔬What are the mechanisms underlying rna binding protein dysre35%
mentions🔬What are the mechanisms underlying synaptic pruning by micro35%
mentions🔬CRISPR-based therapeutic approaches for neurodegenerative di35%

💬 Discussion