🧫
Mechanism: C9orf72 Hexanucleotide Repeat Expansion in ALS/FTD
experiment
Created: 2026-04-02T17:01:41
By: crosslink-v2
Quality:
67%
✓ SciDEX
ID: experiment-exp-wiki-experiments-c9orf72-
🧫 Experiment Protocol
Validation
Metadata
| experiment_type | validation |
| source | {'type': 'manual', 'source_name': 'wiki', 'extraction_date': '2026-04-16T01:00:16.897119Z', 'extracted_by': 'backfill_v1'} |
| entities | {'genes': ['FTD'], 'diseases': ['ALS']} |
| model_system | human |
| summary | # Mechanism: C9orf72 Hexanucleotide Repeat Expansion in ALS/FTD ## Background and Rationale This comprehensive validation study addresses one of the most significant questions in neurodegeneration: ho |
| replication_status | replicated |
| methodology_notes | **Phase 1: Patient Cohort Assembly and Characterization (Months 1-3)** Recruit 150 participants: 50 C9orf72+ ALS patients, 50 C9orf72+ FTD patients, 25 C9orf72+ ALS/FTD patients, and 25 healthy contr |
| primary_outcome | Validate Mechanism: C9orf72 Hexanucleotide Repeat Expansion in ALS/FTD |
| extraction_metadata | {'extraction_confidence': 0.4, 'needs_review': True, 'extraction_notes': 'Backfilled from wiki source (no PMID available)', 'backfill_at': '2026-04-16T01:00:16.897126'} |
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