NRG1

Understanding Entity Pages

This page aggregates everything SciDEX knows about NRG1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

NRG1 is a gene implicated in neurodegeneration research. Key relationships include: associated with, inhibits, regulates. Associated with ALS, Aging, Als. Connected to 127 entities in the SciDEX knowledge graph.

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graph TD
    NRG1["NRG1"]
    NRG1 -->|"inhibits"| Alzheimer["Alzheimer"]
    NRG1 -->|"inhibits"| Als["Als"]
    NRG1 -->|"inhibits"| Neuropathy["Neuropathy"]
    NRG1 -->|"activates"| Aging["Aging"]
    NRG1 -->|"activates"| Depression["Depression"]
    NRG1 -->|"activates"| Cardiovascular["Cardiovascular"]
    NRG1 -->|"activates"| Epilepsy["Epilepsy"]
    NRG1 -->|"activates"| Schizophrenia["Schizophrenia"]
    NRG1 -->|"activates"| Ms["Ms"]
    ERBB4["ERBB4"] -->|"contributes to"| NRG1
    RET["RET"] -->|"inhibits"| NRG1
    ERBB2["ERBB2"] -->|"inhibits"| NRG1
    GENES["GENES"] -->|"inhibits"| NRG1
    ERBB3["ERBB3"] -->|"inhibits"| NRG1
    DISC1["DISC1"] -->|"inhibits"| NRG1
    GLUD1["GLUD1"] -->|"inhibits"| NRG1
    LC3B["LC3B"] -->|"regulates"| NRG1
    MITOPHAGY["MITOPHAGY"] -->|"regulates"| NRG1