Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about DBH: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | DBH |
| Full Name | DBH |
| Chromosome | 9q34.2 |
| Protein Type | Gene |
| Function | DBH catalyzes the oxidative hydroxylation of dopamine to produce norepinephrine. |
| Subcellular Localization | the Golgi apparatus and secretory vesicles of noradrenergic and adrenergic neurons. DBH deficiency |
| Molecular Weight | 73 kDa |
| Amino Acids | 603 aa |
| NCBI Gene ID | Search NCBI |
| GeneCards | DBH |
| Human Protein Atlas | DBH |
| Associated Diseases | ALS |
| Interactions | ERBB4, IL1RL1, IL33, NRG1, ADRA1A, ADRA2A |
| KG Connections | 12 knowledge graph edges |
| Databases | GeneCardsUniProtHPASTRING |
Knowledge base pages for this entity
graph TD
DBH["DBH"] -->|"associated_with"| ALS["ALS"]
DBH["DBH"] -->|"co_expressed_with"| ERBB4["ERBB4"]
DBH["DBH"] -->|"co_expressed_with"| IL1RL1["IL1RL1"]
ADRA1A["ADRA1A"] -->|"co_expressed_with"| DBH["DBH"]
ADRA2A["ADRA2A"] -->|"co_expressed_with"| DBH["DBH"]
DBH["DBH"] -->|"implicated_in"| neurodegeneration["neurodegeneration"]
style DBH fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||