gene

arnt2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about arnt2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

29Connections

0Hypotheses

0Analyses

3Outgoing

4Incoming

No summary available yet. View on Wiki →

🧬 Gene Info

Gene Symbol	ARNT2
Full Name	Aryl Hydrocarbon Receptor Nuclear Translocator 2
Aliases	ARNT2 gene
Chromosome	15q21.3
Function	encodes a critical bHLH-PAS (basic Helix-Loop-Helix-Period Arnt-Single-minded) domain transcription factor that serves as a shared partner for multiple hypoxia-sensitive and circadian rhythm regula...
Molecular Weight	79 kDa
Amino Acids	710 aa
Exons	24
UniProt ID	Q9W2E6
NCBI Gene ID	10638
Ensembl ID	ENSG00000150457
OMIM	606994
GeneCards	ARNT2
Human Protein Atlas	ARNT2
Associated Diseases	neurodegeneration
KG Connections	3 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: arnt2 — AlphaFold Q9W2E6 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (8)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    ARNT2["ARNT2"]
    ARNT2 -->|"target for"| Cancer["Cancer"]
    ARNT2 -->|"expressed in"| SST["SST"]
    ARNT2 -->|"regulates"| Interneuron["Interneuron"]
    ARNT2 -->|"regulates"| Neuron["Neuron"]
    ARNT2 -->|"activates"| Pyramidal["Pyramidal"]
    ARNT2 -->|"regulates"| AND["AND"]
    ARNT2 -->|"inhibits"| ACC["ACC"]
    SST -->|"activates"| ARNT2
    ACC -->|"inhibits"| ARNT2

Outgoing (25)

Target	Relation	Type	Str
INTERNEURONS	regulates	concept	0.50
Cortex	inhibits	brain_region	0.50
INTERNEURONS	activates	concept	0.50

Incoming (4)

Source	Relation	Type	Str
SST	activates	gene	0.60
ACC	inhibits	gene	0.60
ACC	expressed_in	gene	0.60
benchmark_ot_ad_answer_key:ARNT2	data_in	dataset_row	0.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

arnt2

Understanding Entity Pages

Wiki Pages (8)

NPAS3 Gene

ARNT2 - Aryl Hydrocarbon Receptor Nuclear Translocator 2

NPAS4 Gene

NPAS1 - Neuronal PAS Domain Protein 1

ARNT - Aryl Hydrocarbon Receptor Nuclear Translocator

NPAS3 Protein