Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ataxia-telangiectasia: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet. View on Wiki →
No AI portrait yet
Knowledge base pages for this entity
graph TD
ATAXIA_TELANGIECTASIA["ATAXIA-TELANGIECTASIA"]
ATAXIA_TELANGIECTASIA -->|"activates"| CGAS["CGAS"]
ATAXIA_TELANGIECTASIA -->|"activates"| STING["STING"]
ATAXIA_TELANGIECTASIA -->|"regulates"| ATM["ATM"]
ATAXIA_TELANGIECTASIA -->|"activates"| PARKINSON["PARKINSON"]
ATAXIA_TELANGIECTASIA -->|"activates"| amyotrophic_lateral_sclerosis["amyotrophic lateral sclerosis"]
ATAXIA_TELANGIECTASIA -->|"activates"| Parkinson_s_Disease["Parkinson's Disease"]
cGAS_STING["cGAS-STING"] -->|"involved_in"| ATAXIA_TELANGIECTASIA| Target | Relation | Type | Str |
|---|---|---|---|
| CGAS | activates | entity | 0.60 |
| STING | activates | entity | 0.60 |
| ATM | regulates | entity | 0.60 |
| CGAS | activates | protein | 0.50 |
| STING | activates | gene | 0.50 |
| CELL CYCLE | regulates | cell_type | 0.50 |
| Ataxia | regulates | disease | 0.50 |
| Macrophage | regulates | cell_type | 0.50 |
| DNA DAMAGE | regulates | concept | 0.50 |
| Dna Damage Response | regulates | pathway | 0.50 |
| PARKINSON | activates | gene | 0.50 |
| amyotrophic lateral sclerosis | activates | gene | 0.50 |
| Parkinson's Disease | activates | disease | 0.50 |
| Cgas-Sting | activates | pathway | 0.50 |
| Ataxia | activates | disease | 0.50 |
| disease | activates | disease | 0.50 |
| PARKINSON'S | activates | concept | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| cGAS-STING | involved_in | pathway | 0.85 |
| Cgas-Sting Pathway | contributes_to | pathway | 0.85 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity