gene

BST1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about BST1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

21Connections
0Hypotheses
0Analyses
19Outgoing
2Incoming

Summary

Page for BST1 Gene - Bone Marrow Stromal Cell Antigen 1

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🧬 Gene Info
Gene SymbolBST1
Full NameBone Marrow Stromal Cell Antigen 1
AliasesPage for BST1 Gene
Chromosome4p15.2
FunctionBST1/CD157 is expressed primarily on the surface of hematopoietic cells, including neutrophils, monocytes, and bone marrow stromal cells.
Primary ExpressionBone marrow, hematopoietic cells, brain (low)
Molecular Weight33.9 kDa
Amino Acids310 aa
UniProt IDQ15833
NCBI Gene ID682
Ensembl IDENSG00000105552
OMIM615197
GeneCardsBST1
Human Protein AtlasBST1
Associated DiseasesALS, Alzheimer's disease, Parkinson's disease, neurodegeneration
KG Connections21 knowledge graph edges
DatabasesGeneCardsHPASTRING
🔮 Predicted Structure: BST1 — AlphaFold Q15833 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (12)

Knowledge base pages for this entity

Canonical Page

BST1 Gene - Bone Marrow Stromal Cell Antigen 1

gene · 728 words

sporadic-familial-pd-comparison

disease · 3585 words

Multi-Ethnic Parkinson's Disease GWAS

mechanism · 2258 words

Dopaminergic Neurodegeneration

mechanism · 1969 words

lrrk2-protein

protein · 1647 words

Parkinson's Disease Genetic Variants

disease · 1462 words

Pathway Diagram

flowchart TD
    N0["BST1"]
    N1["Parkinson's Disease"]
    N0 -->|"therapeutic target"| N1
    N2["CR2"]
    N0 -->|"causes"| N2
    N3["ERBB1"]
    N0 -->|"causes"| N3
    N4["GPNMB"]
    N0 -->|"causes"| N4
    N5["IL34"]
    N0 -->|"causes"| N5
    N6["PILRA"]
    N0 -->|"causes"| N6
    N7["SHARPIN"]
    N0 -->|"causes"| N7

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    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef drug fill:#1a2a2a,stroke:#26c6da,color:#e0e0e0
    classDef cell_type fill:#2a1a2a,stroke:#ab47bc,color:#e0e0e0
    classDef phenotype fill:#2a2a1a,stroke:#ffa726,color:#e0e0e0
    classDef process fill:#1a2a2a,stroke:#66bb6a,color:#e0e0e0
    classDef biological_process fill:#1a2a2a,stroke:#66bb6a,color:#e0e0e0
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    classDef entity fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef therapeutic fill:#1a2a2a,stroke:#26c6da,color:#e0e0e0
    classDef index fill:#1a1a2a,stroke:#7986cb,color:#e0e0e0
    class N0 gene
    class N1 disease
    class N2 gene
    class N3 gene
    class N4 gene
    class N5 gene
    class N6 gene
    class N7 gene

Outgoing (19)

TargetRelationTypeStr
Parkinson's Diseasetherapeutic_targetdisease0.85
Parkinson'S Diseasetherapeutic_targetdisease0.85
CR2causesgene0.60
ERBB1causesgene0.60
GPNMBcausesgene0.60

Incoming (2)

SourceRelationTypeStr
ATXN3causesgene0.60
B4GALNT1causesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found