IL34

Understanding Entity Pages

This page aggregates everything SciDEX knows about IL34: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

IL34 Gene

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flowchart TD
    N0["IL34"]
    N1["ATXN3"]
    N1 -->|"causes"| N0
    N2["Alzheimer's Disease"]
    N0 -->|"therapeutic target"| N2
    N3["JAK2"]
    N0 -->|"activates"| N3
    N4["STAT3"]
    N0 -->|"activates"| N4
    N5["JAK-STAT signaling"]
    N0 -->|"participates in"| N5
    N6["PILRA"]
    N0 -->|"causes"| N6
    N7["SHARPIN"]
    N0 -->|"causes"| N7
    N8["STX6"]
    N0 -->|"causes"| N8

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef drug fill:#1a2a2a,stroke:#26c6da,color:#e0e0e0
    classDef cell_type fill:#2a1a2a,stroke:#ab47bc,color:#e0e0e0
    classDef phenotype fill:#2a2a1a,stroke:#ffa726,color:#e0e0e0
    classDef process fill:#1a2a2a,stroke:#66bb6a,color:#e0e0e0
    classDef biological_process fill:#1a2a2a,stroke:#66bb6a,color:#e0e0e0
    classDef concept fill:#1a1a2a,stroke:#7986cb,color:#e0e0e0
    classDef entity fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef therapeutic fill:#1a2a2a,stroke:#26c6da,color:#e0e0e0
    classDef index fill:#1a1a2a,stroke:#7986cb,color:#e0e0e0
    class N0 gene
    class N1 gene
    class N2 disease
    class N3 gene
    class N4 gene
    class N5 pathway
    class N6 gene
    class N7 gene
    class N8 gene