Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about FBL: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Ribosome Biogenesis | involved_in | process | 0.95 |
| ALS/FTD | contributes_to | disease | 0.95 |
| ribosome biogenesis | regulates | process | 0.95 |
| Alzheimer'S Disease | contributes_to | disease | 0.95 |
| Apoptosis | regulates | process | 0.95 |
| apoptosis | mediates | process | 0.95 |
| TP53 | activates | gene | 0.90 |
| rRNA processing | regulates | process | 0.90 |
| Ribosome Biogenesis | regulates | process | 0.90 |
| Rrna Processing | regulates | process | 0.90 |
| Nucleolar Stress Response | regulates | pathway | 0.90 |
| Neurodegeneration | involved_in | disease | 0.90 |
| Neuronal Death | causes | phenotype | 0.85 |
| Neurodegeneration | implicated_in | disease | 0.85 |
| Cancer | associated_with | disease | 0.85 |
| Als/Ftd | contributes_to | disease | 0.80 |
| apoptosis resistance | promotes | phenotype | 0.80 |
| Alzheimer's Disease | contributes_to | disease | 0.80 |
| Als/Ftd | implicated_in | disease | 0.75 |
| translational control | modulates | process | 0.75 |
| Alzheimer's Disease | implicated_in | disease | 0.75 |
| breast cancer | associated_with | disease | 0.70 |
| hepatocellular carcinoma | associated_with | disease | 0.70 |
| TP53 | interacts_with | protein | 0.70 |
| breast cancer | drives | disease | 0.70 |
| hepatocellular carcinoma | drives | disease | 0.70 |
| apoptosis | regulates | process | 0.70 |
| Alzheimer's disease | associated_with | disease | 0.70 |
| neurodegeneration | associated_with | disease | 0.60 |
| MDM2 | activates | gene | 0.60 |
| neurodegeneration | regulates | disease | 0.60 |
| oxidative stress response | participates_in | pathway | 0.60 |
| apoptosis pathway | participates_in | pathway | 0.60 |
| Alzheimer's disease | activates | disease | 0.60 |
| frontotemporal dementia | activates | disease | 0.60 |
| neurons | expressed_in | cell_type | 0.60 |
| RNA | inhibits | gene | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| cellular stressors | modulates | process | 0.80 |
| Cellular Stressors | modulates | mechanism | 0.80 |
| ALS | activates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||