FZD9

Understanding Entity Pages

This page aggregates everything SciDEX knows about FZD9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Gene encoding the Frizzled-9 receptor, a key component of Wnt signaling pathways involved in neurodevelopment, synaptic plasticity, and neurodegenerative disease.

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graph TD
    FZD9["<b>FZD9</b>"]
    Als{"Als"}
    FZD9 -->|"regulates"| Als
    Ms{"Ms"}
    FZD9 -->|"regulates"| Ms
    Amyotrophic_Lateral_Sclerosis{"Amyotrophic Lateral Sclerosis"}
    FZD9 -->|"regulates"| Amyotrophic_Lateral_Sclerosis
    FZD2["FZD2"]
    FZD9 -->|"regulates"| FZD2
    GRB2["GRB2"]
    FZD9 -->|"regulates"| GRB2
    AMYOTROPHIC_LATERAL_SCLEROSIS["AMYOTROPHIC LATERAL SCLEROSIS"]
    FZD9 -->|"regulates"| AMYOTROPHIC_LATERAL_SCLEROSIS
    ALS["ALS"]
    FZD9 -->|"regulates"| ALS
    EIF2AK2["EIF2AK2"]
    FZD9 -->|"regulates"| EIF2AK2
    CREBBP["CREBBP"]
    FZD9 -->|"regulates"| CREBBP
    Wnt(["Wnt"])
    FZD9 -->|"regulates"| Wnt
    neurodegeneration["neurodegeneration"]
    FZD9 -->|"implicated in"| neurodegeneration
    PIK3CA["PIK3CA"]
    PIK3CA -->|"regulates"| FZD9
    CD44["CD44"]
    CD44 -->|"regulates"| FZD9
    MOTOR_NEURONS["MOTOR NEURONS"]
    MOTOR_NEURONS -->|"regulates"| FZD9
    SRC["SRC"]
    SRC -->|"regulates"| FZD9
    EEF2["EEF2"]
    EEF2 -->|"regulates"| FZD9
    SOD1["SOD1"]
    SOD1 -->|"regulates"| FZD9
    style FZD9 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0