Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GLUTAMATE EXCITOTOXICITY: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| NLRP3 INFLAMMASOME | associated_with | pathway | 0.50 |
| RIVASTIGMINE | associated_with | drug | 0.45 |
| GALANTAMINE | associated_with | drug | 0.45 |
| HIPPOCAMPUS | associated_with | brain_region | 0.45 |
| DONEPEZIL | associated_with | drug | 0.45 |
| MEMANTINE | associated_with | drug | 0.45 |
| SPINAL CORD | associated_with | brain_region | 0.45 |
| Source | Relation | Type | Str |
|---|---|---|---|
| TET2 | treats | gene | 0.70 |
| BDNF | protects_against | gene | 0.70 |
| GLUTAMATE | causes | phenotype | 0.70 |
| GLUTAMATE | inhibits | phenotype | 0.70 |
| ASTROCYTES | protects_against | cell_type | 0.70 |
| SLC7A11 | regulates | gene | 0.65 |
| STING | causes | gene | 0.65 |
| HIPPOCAMPUS | causes | brain_region | 0.65 |
| HIPPOCAMPUS | activates | brain_region | 0.65 |
| NLRP3 INFLAMMASOME | activates | pathway | 0.65 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||