Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GLOMERULONEPHRITIS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | GLOMERULONEPHRITIS |
Knowledge base pages for this entity
graph TD
GLOMERULONEPHRITIS["GLOMERULONEPHRITIS"]
GLOMERULONEPHRITIS -->|"treats"| Oxidative_Stress["Oxidative Stress"]
GLOMERULONEPHRITIS -->|"treats"| Autophagy["Autophagy"]
GLOMERULONEPHRITIS -->|"treats"| Apoptosis["Apoptosis"]
GLOMERULONEPHRITIS -->|"treats"| Pi3K_Akt["Pi3K/Akt"]
GLOMERULONEPHRITIS -->|"activates"| Oxidative_Phosphorylation["Oxidative Phosphorylation"]
GLOMERULONEPHRITIS -->|"treats"| Inflammation["Inflammation"]
AUTOPHAGY["AUTOPHAGY"] -->|"treats"| GLOMERULONEPHRITIS
APOPTOSIS["APOPTOSIS"] -->|"treats"| GLOMERULONEPHRITIS
OXIDATIVE_STRESS["OXIDATIVE STRESS"] -->|"treats"| GLOMERULONEPHRITIS
PI3K["PI3K"] -->|"treats"| GLOMERULONEPHRITIS
INFLAMMATION["INFLAMMATION"] -->|"treats"| GLOMERULONEPHRITIS
AKT["AKT"] -->|"treats"| GLOMERULONEPHRITIS
CYTOKINES["CYTOKINES"] -->|"activates"| GLOMERULONEPHRITIS
CD68["CD68"] -->|"activates"| GLOMERULONEPHRITIS| Target | Relation | Type | Str |
|---|---|---|---|
| Oxidative Stress | treats | pathway | 0.60 |
| Autophagy | treats | pathway | 0.60 |
| Apoptosis | treats | pathway | 0.60 |
| Pi3K/Akt | treats | pathway | 0.60 |
| Oxidative Phosphorylation | activates | pathway | 0.60 |
| Inflammation | treats | disease | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| PI3K | treats | gene | 0.65 |
| AKT | treats | gene | 0.65 |
| CD68 | activates | gene | 0.65 |
| EGFR | implicated_in | gene | 0.65 |
| AUTOPHAGY | treats | gene | 0.65 |
| APOPTOSIS | treats | gene | 0.65 |
| OXIDATIVE STRESS | treats | gene | 0.65 |
| INFLAMMATION | treats | gene | 0.65 |
| CYTOKINES | activates | gene | 0.65 |
| GENES | activates | gene | 0.65 |
| DNASE2 | associated_with | gene | 0.60 |
| Nephropathy | implicated_in | disease | 0.55 |
| Als | treats | disease | 0.55 |
| Chronic Kidney Disease | implicated_in | disease | 0.55 |
| Lupus | activates | disease | 0.55 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||