KDM5A

Understanding Entity Pages

This page aggregates everything SciDEX knows about KDM5A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Page for KDM5A Protein (Lysine Specific Demethylase 5A (JARID1A))

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graph TD
    KDM5A["<b>KDM5A</b>"]
    TREM2["TREM2"]
    KDM5A -->|"upregulates"| TREM2
    HOXA5["HOXA5"]
    KDM5A -->|"regulates"| HOXA5
    Wnt___catenin_pathway(["Wnt/beta-catenin pathway"])
    KDM5A -->|"activates"| Wnt___catenin_pathway
    KDM5A -->|"inhibits"| Wnt___catenin_pathway
    p53["p53"]
    KDM5A -->|"regulates"| p53
    WTAP["WTAP"]
    KDM5A -->|"upregulates"| WTAP
    PARP1["PARP1"]
    KDM5A -->|"interacts with"| PARP1
    Als{"Als"}
    KDM5A -->|"regulates"| Als
    ALS{"ALS"}
    KDM5A -->|"regulates"| ALS
    CHD4["CHD4"]
    KDM5A -->|"regulates"| CHD4
    GENES["GENES"]
    KDM5A -->|"regulates"| GENES
    AND["AND"]
    KDM5A -->|"interacts with"| AND
    microglia["microglia"]
    microglia -->|"regulates"| KDM5A
    CHD4 -->|"regulates"| KDM5A
    GENES -->|"regulates"| KDM5A
    style KDM5A fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0