MEF2A

Understanding Entity Pages

This page aggregates everything SciDEX knows about MEF2A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

MEF2A is a gene implicated in neurodegeneration research. Key relationships include: inhibits, therapeutic target, associated with. Associated with Aging, Cardiovascular, Ms. Connected to 26 entities in the SciDEX knowledge graph.

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graph TD
    MEF2A["<b>MEF2A</b>"]
    TREM2["TREM2"]
    MEF2A -->|"upregulates"| TREM2
    Senescence{"Senescence"}
    MEF2A -->|"therapeutic target"| Senescence
    Aging{"Aging"}
    MEF2A -->|"inhibits"| Aging
    Ms{"Ms"}
    MEF2A -->|"inhibits"| Ms
    Cardiovascular{"Cardiovascular"}
    MEF2A -->|"therapeutic target"| Cardiovascular
    MEF2A -->|"associated with"| Aging
    MEF2A -->|"inhibits"| Senescence
    MEF2A -->|"inhibits"| Cardiovascular
    AQP1["AQP1"]
    MEF2A -->|"inhibits"| AQP1
    Epigenetic(["Epigenetic"])
    MEF2A -->|"therapeutic target"| Epigenetic
    Angiogenesis(["Angiogenesis"])
    MEF2A -->|"inhibits"| Angiogenesis
    DNA["DNA"]
    MEF2A -->|"inhibits"| DNA
    OxPC["OxPC"]
    OxPC -->|"activates"| MEF2A
    HDAC4["HDAC4"]
    HDAC4 -->|"inhibits"| MEF2A
    AMPK["AMPK"]
    AMPK -->|"associated with"| MEF2A
    AQP1 -->|"inhibits"| MEF2A
    DNA -->|"inhibits"| MEF2A
    AMPK -->|"inhibits"| MEF2A
    AND["AND"]
    AND -->|"inhibits"| MEF2A
    AGING["AGING"]
    AGING -->|"inhibits"| MEF2A
    style MEF2A fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0