Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SGLT2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Glucose Reabsorption | regulates | process | 0.95 |
| type 2 diabetes | biomarker_for | disease | 0.90 |
| glucose metabolism | involved_in | process | 0.90 |
| MTOR | regulates | protein | 0.70 |
| mTOR | regulates | protein | 0.70 |
| ferroptosis | participates_in | pathway | 0.60 |
| VDAC1 | inhibits | gene | 0.60 |
| neurodegeneration | inhibits | disease | 0.60 |
| oxidative stress response | participates_in | pathway | 0.60 |
| lipid metabolism | participates_in | pathway | 0.60 |
| senescence | participates_in | pathway | 0.60 |
| Parkinson's disease | inhibits | disease | 0.60 |
| stem cells | expressed_in | cell_type | 0.55 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||