concept

SURVIVIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SURVIVIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

36Connections
0Hypotheses
0Analyses
15Outgoing
10Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameSURVIVIN
Key Genes/ProteinsGABPB1, AURKA, AND, FOXP1, CANCER, FBXL7
Related DiseasesCancer, Aging
Related PathwaysUbiquitin-Proteasome, Cell Cycle, Proteasome

Wiki Pages (20)

Knowledge base pages for this entity

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Pathway Diagram

graph TD
    SURVIVIN["SURVIVIN"]
    SURVIVIN -->|"binds"| FBXL7["FBXL7"]
    SURVIVIN -->|"promotes"| Drug_Resistance["Drug Resistance"]
    SURVIVIN -.biomarker for.-> Gastric_Cancer_Prognosis["Gastric Cancer Prognosis"]
    SURVIVIN -->|"inhibits"| Apoptosis["Apoptosis"]
    SURVIVIN -->|"activates"| Cancer["Cancer"]
    SURVIVIN -->|"activates"| Aging["Aging"]
    SURVIVIN -->|"activates"| AND["AND"]
    AURKA["AURKA"] -->|"upregulates"| SURVIVIN
    FBXL7 -->|"degrades"| SURVIVIN
    GABPB1["GABPB1"] -->|"regulates"| SURVIVIN
    DNA["DNA"] -->|"activates"| SURVIVIN

Outgoing (20)

TargetRelationTypeStr
Canceractivatesdisease0.65
Agingactivatesdisease0.65
Cancertherapeutic_targetdisease0.65
ANDactivatesgene0.60
FOXP1regulatesgene0.60

Incoming (16)

SourceRelationTypeStr
GABPB1regulatesgene0.80
AURKAregulates_stability_by_targeting_FBXL7gene0.80
AURKAactivatesgene0.60
DNAactivatesgene0.60
FBXL7regulatesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found