Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SYNAPTIC PLASTICITY GENES: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | SYNAPTIC PLASTICITY GENES |
Knowledge base pages for this entity
graph TD
SYNAPTIC_PLASTICITY_GENES["SYNAPTIC PLASTICITY GENES"]
SYNAPTIC_PLASTICITY_GENES -->|"studied_in"| neurodegeneration["neurodegeneration"]
SYNAPTIC_PLASTICITY_GENES -->|"interacts"| BDNF["BDNF"]
SYNAPTIC_PLASTICITY_GENES -->|"interacts"| CREB1["CREB1"]
BDNF -->|"interacts"| SYNAPTIC_PLASTICITY_GENES
CREB1 -->|"interacts"| SYNAPTIC_PLASTICITY_GENES
Longevity_and_Rejuvenation_The["Longevity and Rejuvenation Therapies Landscape"] -->|"references"| SYNAPTIC_PLASTICITY_GENES
Epigenetic_Therapies_for_Neuro["Epigenetic Therapies for Neurodegeneration"] -->|"references"| SYNAPTIC_PLASTICITY_GENES
SPAM1__SIRT6_Positive_Alloster["SPAM1: SIRT6 Positive Allosteric Modulator"] -->|"references"| SYNAPTIC_PLASTICITY_GENES
Epigenetic_Editing_and_CRISPR_["Epigenetic Editing and CRISPR Approaches in CBS/PSP"] -->|"references"| SYNAPTIC_PLASTICITY_GENES
Section_192_Advanced_Epigenomi["Section 192 Advanced Epigenomics and Chromatin Therapy in CBS/PSP"] -->|"references"| SYNAPTIC_PLASTICITY_GENES
ONO_2020_for_Alzheimer_s_Disea["ONO-2020 for Alzheimer's Disease (NCT06881836)"] -->|"references"| SYNAPTIC_PLASTICITY_GENES| Target | Relation | Type | Str |
|---|---|---|---|
| neurodegeneration | associated_with | disease | 0.48 |
| BDNF | interacts_with | gene | 0.48 |
| CREB1 | interacts_with | gene | 0.48 |
| CREB1 | co_discussed | gene | 0.40 |
| HMGCR | co_discussed | gene | 0.40 |
| mitochondrial biogenesis genes | co_discussed | gene | 0.40 |
| Disease-causing mutations with integrated reporters | co_discussed | gene | 0.40 |
| NURR1 | co_discussed | gene | 0.40 |
| BDNF | co_discussed | gene | 0.40 |
| HTT | co_discussed | gene | 0.40 |
| SIRT1 | co_discussed | gene | 0.40 |
| LDLR | co_discussed | gene | 0.40 |
| APOE regulatory regions | co_discussed | gene | 0.40 |
| FOXO3 | co_discussed | gene | 0.40 |
| Cell-type-specific essential genes | co_discussed | gene | 0.40 |
| APOE | co_discussed | gene | 0.40 |
| PITX3 | co_discussed | gene | 0.40 |
| neuronal identity transcription factors | co_discussed | gene | 0.40 |
| benchmark_ot_ad_answer_key:SYNAPTIC PLASTICITY GENES | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| h-29ef94d5 | targets_gene | hypothesis | 0.90 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||