concept

SYNAPTIC PLASTICITY GENES

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SYNAPTIC PLASTICITY GENES: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

46Connections

1Hypotheses

4Analyses

19Outgoing

27Incoming

0Experiments

4Debates

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💡 Concept Info

Name	SYNAPTIC PLASTICITY GENES

Pathway Diagram

graph TD
    SYNAPTIC_PLASTICITY_GENES["SYNAPTIC PLASTICITY GENES"]
    SYNAPTIC_PLASTICITY_GENES -->|"studied_in"| neurodegeneration["neurodegeneration"]
    SYNAPTIC_PLASTICITY_GENES -->|"interacts"| BDNF["BDNF"]
    SYNAPTIC_PLASTICITY_GENES -->|"interacts"| CREB1["CREB1"]
    BDNF -->|"interacts"| SYNAPTIC_PLASTICITY_GENES
    CREB1 -->|"interacts"| SYNAPTIC_PLASTICITY_GENES
    Longevity_and_Rejuvenation_The["Longevity and Rejuvenation Therapies Landscape"] -->|"references"| SYNAPTIC_PLASTICITY_GENES
    Epigenetic_Therapies_for_Neuro["Epigenetic Therapies for Neurodegeneration"] -->|"references"| SYNAPTIC_PLASTICITY_GENES
    SPAM1__SIRT6_Positive_Alloster["SPAM1: SIRT6 Positive Allosteric Modulator"] -->|"references"| SYNAPTIC_PLASTICITY_GENES
    Epigenetic_Editing_and_CRISPR_["Epigenetic Editing and CRISPR Approaches in CBS/PSP"] -->|"references"| SYNAPTIC_PLASTICITY_GENES
    Section_192_Advanced_Epigenomi["Section 192 Advanced Epigenomics and Chromatin Therapy in CBS/PSP"] -->|"references"| SYNAPTIC_PLASTICITY_GENES
    ONO_2020_for_Alzheimer_s_Disea["ONO-2020 for Alzheimer's Disease (NCT06881836)"] -->|"references"| SYNAPTIC_PLASTICITY_GENES

Outgoing (19)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:SYNAPTIC PLASTICITY GENES	data_in	dataset_row	0.00
neurodegeneration	associated_with	disease	0.48
BDNF	interacts_with	gene	0.48
CREB1	interacts_with	gene	0.48
NURR1	co_discussed	gene	0.40
BDNF	co_discussed	gene	0.40
HTT	co_discussed	gene	0.40
SIRT1	co_discussed	gene	0.40
LDLR	co_discussed	gene	0.40
APOE regulatory regions	co_discussed	gene	0.40
FOXO3	co_discussed	gene	0.40
Cell-type-specific essential genes	co_discussed	gene	0.40
APOE	co_discussed	gene	0.40
PITX3	co_discussed	gene	0.40
neuronal identity transcription factors	co_discussed	gene	0.40
CREB1	co_discussed	gene	0.40
HMGCR	co_discussed	gene	0.40
mitochondrial biogenesis genes	co_discussed	gene	0.40
Disease-causing mutations with integrated reporters	co_discussed	gene	0.40

Incoming (27)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:SYNAPTIC PLASTICITY GENES	data_in	dataset_row	0.00
h-29ef94d5	targets_gene	hypothesis	0.90
miR-132-3p	regulates	gene	0.70
H3K27me3	regulates	biomarker	0.70
EZH2	represses	enzyme	0.70
EZH2	inhibits	protein	0.70
BDNF	interacts_with	gene	0.48
CREB1	interacts_with	gene	0.48
BDNF	co_discussed	gene	0.40
LDLR	co_discussed	gene	0.40
Cell-type-specific essential genes	co_discussed	gene	0.40
SIRT1	co_discussed	gene	0.40
HTT	co_discussed	gene	0.40
APOE regulatory regions	co_discussed	gene	0.40
NURR1	co_discussed	gene	0.40
FOXO3	co_discussed	gene	0.40
PGC1A	co_discussed	gene	0.40
DMPK	co_discussed	gene	0.40
neuronal identity transcription factors	co_discussed	gene	0.40
ONO-2020 for Alzheimer's Disease (NCT06881836)	references	clinical	0.40
APOE	co_discussed	gene	0.40
HDAC4 Protein	references	protein	0.40
MAX Protein (MAX)	references	protein	0.40
CREB1	co_discussed	gene	0.40
NRSF Protein	references	protein	0.40
repeat-containing transcripts	co_discussed	gene	0.40
PITX3	co_discussed	gene	0.40