Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about VEGFR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | VEGFR |
Knowledge base pages for this entity
graph TD
VEGFR["VEGFR"]
VEGFR -->|"activates"| Cancer["Cancer"]
VEGFR -->|"activates"| Pyroptosis["Pyroptosis"]
VEGFR -->|"activates"| Adaptive_Immunity["Adaptive Immunity"]
VEGFR -->|"activates"| Immune_Response["Immune Response"]
VEGFR -->|"activates"| Autophagy["Autophagy"]
VEGFR -->|"activates"| Inflammasome["Inflammasome"]
STING["STING"] -->|"inhibits"| VEGFR
ANGPT1["ANGPT1"] -->|"activates"| VEGFR
PDGFRB["PDGFRB"] -->|"activates"| VEGFR
CD8["CD8"] -->|"activates"| VEGFR
PD_1["PD-1"] -->|"inhibits"| VEGFR
RNA["RNA"] -->|"target for"| VEGFR
LOX_LOXL1_4["LOX/LOXL1-4"] -->|"target for"| VEGFR
LOXL3["LOXL3"] -->|"target for"| VEGFR| Target | Relation | Type | Str |
|---|---|---|---|
| Cancer | activates | disease | 0.60 |
| Cancer | therapeutic_target | disease | 0.60 |
| Pyroptosis | activates | disease | 0.60 |
| Alzheimer | associated_with | disease | 0.60 |
| Als | associated_with | disease | 0.60 |
| Neuroinflammation | associated_with | disease | 0.60 |
| Adaptive Immunity | activates | pathway | 0.55 |
| Immune Response | activates | pathway | 0.55 |
| Autophagy | activates | pathway | 0.55 |
| Inflammasome | activates | pathway | 0.55 |
| Immune Response | associated_with | pathway | 0.55 |
| Blood-Brain Barrier | associated_with | pathway | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| STING | inhibits | gene | 0.60 |
| ANGPT1 | activates | gene | 0.60 |
| PDGFRB | activates | gene | 0.60 |
| CD8 | activates | gene | 0.60 |
| LOX/LOXL1-4 | therapeutic_target | gene | 0.60 |
| VEGF | associated_with | gene | 0.60 |
| VEGFA | inhibits | gene | 0.60 |
| PD-1 | inhibits | gene | 0.60 |
| RNA | therapeutic_target | gene | 0.60 |
| LOXL3 | therapeutic_target | gene | 0.60 |
| AUTOPHAGY | activates | gene | 0.60 |
| PYROPTOSIS | activates | gene | 0.60 |
| AMPK | activates | gene | 0.60 |
| ALZHEIMER | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||