Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about WNT PATHWAY: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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graph TD
WNT_PATHWAY[WNT PATHWAY]
WNT_PATHWAY -->|involved_in| Tumor_Growth[Tumor Growth]
WNT_PATHWAY -->|regulates| stem_cells[stem cells]
WNT_PATHWAY -->|involved_in| Tumor_Invasion[Tumor Invasion]
WNT_PATHWAY -->|causes| cancer[cancer]
WNT_PATHWAY -->|participates in| ESCC[ESCC]
WNT3A[WNT3A] -->|activates| WNT_PATHWAY
GEFITINIB[GEFITINIB] -->|activates| WNT_PATHWAY
TAU_PHOSPHORYLATION[TAU PHOSPHORYLATION] -->|regulates| WNT_PATHWAY| Target | Relation | Type | Str |
|---|---|---|---|
| Tumor Growth | involved_in | process | 0.90 |
| stem cells | regulates | cell_type | 0.90 |
| Tumor Invasion | involved_in | process | 0.85 |
| cancer | causes | disease | 0.80 |
| ESCC | participates_in | disease | 0.70 |
| WNT3A | associated_with | gene | 0.50 |
| ASTROCYTES | associated_with | cell_type | 0.50 |
| STEM CELLS | associated_with | cell_type | 0.50 |
| NEURONS | associated_with | cell_type | 0.50 |
| GEFITINIB | associated_with | drug | 0.50 |
| HIPPOCAMPUS | associated_with | brain_region | 0.45 |
| CORTEX | associated_with | brain_region | 0.45 |
| TAU | associated_with | protein | 0.45 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Glioblastoma Multiforme | associated_with | disease | 0.95 |
| WNT3A | activates | gene | 0.70 |
| GEFITINIB | activates | drug | 0.65 |
| TAU PHOSPHORYLATION | regulates | phenotype | 0.65 |
| OLIGODENDROCYTES | associated_with | cell_type | 0.50 |
| NEURAL STEM CELLS | associated_with | cell_type | 0.50 |
| NEUROGENESIS | associated_with | phenotype | 0.50 |
| ENTORHINAL CORTEX | associated_with | brain_region | 0.45 |
| TEMPORAL LOBE | associated_with | brain_region | 0.45 |
| TAU PHOSPHORYLATION | associated_with | phenotype | 0.45 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity