Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NEURAL STEM CELLS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | NEURAL STEM CELLS |
| Key Genes/Proteins | TET2, BDNF, MYC, AQP4 |
| Related Diseases | AUTOPHAGY, NEUROGENESIS |
| Related Pathways | WNT SIGNALING, WNT PATHWAY |
Knowledge base pages for this entity
graph TD
NEURAL_STEM_CELLS["NEURAL STEM CELLS"]
NEURAL_STEM_CELLS -->|"treats"| Neurological_Disorders["Neurological Disorders"]
NEURAL_STEM_CELLS -->|"treats"| Multiple_Sclerosis["Multiple Sclerosis"]
NEURAL_STEM_CELLS -->|"modulates"| Inflammation["Inflammation"]
NEURAL_STEM_CELLS -->|"treats"| Alzheimer_S_Disease["Alzheimer'S Disease"]
NEURAL_STEM_CELLS -->|"treats"| Parkinson_S_Disease["Parkinson'S Disease"]
NEURAL_STEM_CELLS -->|"treats"| Amyotrophic_Lateral_Sclerosis["Amyotrophic Lateral Sclerosis"]
SOX2["SOX2"] -->|"regulates"| NEURAL_STEM_CELLS
FIP200["FIP200"] -->|"regulates"| NEURAL_STEM_CELLS
TAX1BP1["TAX1BP1"] -->|"regulates"| NEURAL_STEM_CELLS
PIEZO1["PIEZO1"] -->|"regulates"| NEURAL_STEM_CELLS
TET2["TET2"] -->|"activates"| NEURAL_STEM_CELLS
CHI3L1["CHI3L1"] -->|"inhibits"| NEURAL_STEM_CELLS
autophagic_cell_death["autophagic cell death"] -->|"causes"| NEURAL_STEM_CELLS
AQP4["AQP4"] -->|"inhibits"| NEURAL_STEM_CELLS| Target | Relation | Type | Str |
|---|---|---|---|
| SPINAL CORD | associated_with | brain_region | 0.50 |
| WNT PATHWAY | associated_with | pathway | 0.50 |
| DENTATE GYRUS | associated_with | brain_region | 0.50 |
| WNT SIGNALING | associated_with | pathway | 0.50 |
| CURCUMIN | associated_with | drug | 0.45 |
| Source | Relation | Type | Str |
|---|---|---|---|
| AUTOPHAGY | regulates | phenotype | 0.70 |
| TET2 | causes | gene | 0.70 |
| BDNF | interacts_with | gene | 0.70 |
| WNT SIGNALING | activates | pathway | 0.70 |
| NEUROGENESIS | activates | phenotype | 0.70 |
| MYC | activates | gene | 0.70 |
| AQP4 | inhibits | gene | 0.65 |
| FIBROBLASTS | activates | cell_type | 0.65 |
| CURCUMIN | associated_with | drug | 0.45 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||