Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ACUTE LUNG INJURY: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | ACUTE LUNG INJURY |
Knowledge base pages for this entity
graph TD
ACUTE_LUNG_INJURY["ACUTE LUNG INJURY"]
ACUTE_LUNG_INJURY -->|"upregulates"| SERPINE1["SERPINE1"]
ZBP1["ZBP1"] -->|"promotes"| ACUTE_LUNG_INJURY
Cirp_Zbp1_Panoptosis_Pathway["Cirp-Zbp1-Panoptosis Pathway"] -->|"contributes to"| ACUTE_LUNG_INJURY
LPS["LPS"] -->|"causes"| ACUTE_LUNG_INJURY
Sepsis["Sepsis"] -->|"causes"| ACUTE_LUNG_INJURY
lactate["lactate"] -->|"promotes"| ACUTE_LUNG_INJURY
NETs["NETs"] -->|"contributes to"| ACUTE_LUNG_INJURY
Nets["Nets"] -->|"contributes to"| ACUTE_LUNG_INJURY
PANoptosis["PANoptosis"] -->|"contributes to"| ACUTE_LUNG_INJURY| Target | Relation | Type | Str |
|---|---|---|---|
| SERPINE1 | upregulates | protein | 0.75 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ZBP1 | promotes | protein | 0.95 |
| Cirp-Zbp1-Panoptosis Pathway | contributes_to | pathway | 0.95 |
| lactate | promotes | metabolite | 0.90 |
| NETs | contributes_to | process | 0.90 |
| Nets | contributes_to | process | 0.90 |
| Lactic Acidemia | associated_with | phenotype | 0.90 |
| Sepsis | causes | disease | 0.90 |
| PANoptosis | contributes_to | process | 0.85 |
| PCTR1 | treats | compound | 0.85 |
| Lactic Acidemia | promotes | phenotype | 0.85 |
| ferroptosis | contributes_to | process | 0.85 |
| Lactate | risk_factor_for | compound | 0.80 |
| PI3K | regulates | pathway | 0.80 |
| Mitochondrial Transfer | protects_against | process | 0.80 |
| PAD4 | involved_in | gene | 0.80 |
| CIRP | biomarker_for | protein | 0.75 |
| TRKB | treats | protein | 0.70 |
| STAT3 | associated_with | protein | 0.70 |
| BDNF | treats | protein | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||