gene 1,159 words KG: BMP4
Contents

BMP4 Gene (Bone Morphogenetic Protein 4)

🧬 Gene Info
Gene SymbolBMP4
Functionencodes a member of the TGF-beta superfamily of signaling molecules.
Molecular Weight47 kDa
Amino Acids116 aa
PathwaysMAPK Pathway, PI3K, TGF-β
Ensembl IDENSG00000109475
GeneCardsBMP4
Human Protein AtlasBMP4
Signal peptide cleavageN-terminal targeting sequence removed
Prodomain removalCleavage to generate active mature protein
Dimer formationActive form is a homodimer (or heterodimer with BMP2)
Associated DiseasesALZHEIMER'S DISEASE, Cancer, Carcinoma, Ms, Tumor
InteractionsAND, APOE4, BMP7, HEDGEHOG, MICROGLIA, TGFB2
KG Connections49 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

BMP4 Pathway Inhibition for Oligodendrocyte Myelination Supp
Score: 0.54

Knowledge Graph (12 edges)

TGFBR2 associated_with BMP4
BMP4 associated_with MYC
BMP4 associated_with E2F5
BMP4 associated_with CDKN2B
BMP4 activates TGFBR1
BMP4 associated_with BMP2
BMP4 activates TGFB2
BMP4 activates BMP7
MICROGLIA interacts_with BMP4
BMP2 associated_with BMP4

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.