gene 1,159 words KG: BMP4 2026-03-26
kind:genesection:genestopic:alzheimerstopic:parkinsonstopic:autism
Contents

BMP4 Gene (Bone Morphogenetic Protein 4)

🧬 Gene Info
Gene SymbolBMP4
Functionencodes a member of the TGF-beta superfamily of signaling molecules.
Molecular Weight47 kDa
Amino Acids116 aa
PathwaysMAPK Pathway, PI3K, TGF-β
Ensembl IDENSG00000109475
GeneCardsBMP4
Human Protein AtlasBMP4
Associated DiseasesALZHEIMER'S DISEASE, Cancer, Carcinoma, Ms, Tumor
InteractionsTGFBR1, TGFB2, BMP7, TREM2, HEDGEHOG, APOE4
KG Connections45 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (7)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.52
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
TREM2-mediated microglial tau clearance enhancement
Score: 0.49
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (11)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Cell type vulnerability in Alzheimer's Disease (SEA-AD data
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

See Also (13)

Hedgehog Signaling in Neurodegeneration
mechanism · KG edge: inhibits
Fibroblast Growth Factor Signaling in Neurodegeneration
mechanism · KG edge: activates
Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: therapeutic_target
TGFBR1 — TGF-beta Receptor 1
gene · KG edge: activates
TGFB2 Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

BMP4 associated_with MYC
BMP4 associated_with E2F5
BMP4 associated_with CDKN2B
BMP4 activates TGFBR1
BMP4 associated_with BMP2
BMP4 activates TGFB2
BMP4 activates BMP7
BMP4 interacts_with Tgf-Beta
BMP4 regulates SHH
BMP4 regulates TREM2