gene 1,147 words KG: BMP7 2026-03-26
kind:genesection:genestopic:alzheimerstopic:parkinsonstopic:kidney-disease
Contents

BMP7 Gene (Bone Morphogenetic Protein 7)

🧬 Gene Info
Gene SymbolBMP7
Functionencodes a member of the TGF-beta superfamily of signaling molecules.
Primary Expressionadult tissues and has important roles in bone formation, kidney development, tissue repair, and neuroprotection
Amino Acids431 aa
PathwaysMAPK pathway, PI3K
Ensembl IDENSG00000101144
GeneCardsBMP7
Human Protein AtlasBMP7
Associated DiseasesAls, Alzheimer, Autoimmune, Cancer, Carcinoma, Diabetes
InteractionsTGFB2, BMP4, TGFBR1, ERK1, BMPR1B, ERK
KG Connections62 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (7)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.50
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42

Related Analyses (7)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (13)

Packard Center for ALS Research
institution · KG edge: associated_with
Alzheimer Indonesia
institution · KG edge: associated_with
CX3CR1 Modulation Therapy for Neurodegeneration
idea · KG edge: associated_with
Autoimmune Hypothesis in Alzheimer's Disease
hypothesis · KG edge: associated_with
EP300 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

BMP7 regulates Astrocyte
BMP7 associated_with CX3CR1
BMP7 associated_with AHR
BMP7 associated_with EP300
BMP7 associated_with JUN
BMP7 associated_with JAK2
BMP7 associated_with CCL20
BMP7 associated_with CD38
BMP7 associated_with FOXP3
BMP7 associated_with PPARG