gene 524 words KG: TGFBR1 2026-03-24
kind:genesection:genesstate:published
Contents

TGFBR1 — TGF-beta Receptor 1

🧬 Gene Info
Gene SymbolTGFBR1
Full NameTransforming Growth Factor Beta Receptor 1
AliasesTGF-beta Receptor 1
Chromosome9q22
Protein TypeReceptor
FunctionTGFBR1 encodes the Type I TGF-beta receptor, a serine/threonine protein kinase that mediates the signaling of transforming growth factor-beta (TGF-β) family cytokines.
Amino Acids567 aa
PathwaysTGF-β, TGF-β signaling
UniProt IDP36897
NCBI Gene ID7046
Ensembl IDENSG00000106799
OMIM190181
GeneCardsTGFBR1
Human Protein AtlasTGFBR1
Associated DiseasesAls, Cancer, Carcinoma, Ms, Tumor, epilepsy
InteractionsTGFB2, BMP7, PTEN, RAF1, CDC42, ACVR1
KG Connections95 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (5)

Mitochondrial SPM Synthesis Platform Engineering
Score: 0.38
Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.62
Ocular Immune Privilege Extension
Score: 0.47
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.47
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.43

Related Analyses (5)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · completed

See Also (15)

Packard Center for ALS Research
institution · KG edge: associated_with
RAB7A — RAB7A, Member RAS Oncogene Family
gene · KG edge: expressed_in
PIK3CA Gene
gene · KG edge: associated_with
PI3K — Phosphoinositide 3-Kinase
gene · KG edge: interacts_with
MYC Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

TGFBR1 associated_with BMP2
TGFBR1 activates TGFB2
TGFBR1 activates BMP7
TGFBR1 associated_with CDK4
TGFBR1 interacts_with PTEN
TGFBR1 interacts_with RAF1
TGFBR1 interacts_with CDC42
TGFBR1 interacts_with ACVR1
TGFBR1 expressed_in TGFB1
TGFBR1 associated_with E2F5