gene 990 words KG: TGFB2 2026-03-31
kind:genesection:genestopic:alzheimerstopic:parkinsonsstate:published
Contents

TGFB2 Gene

🧬 Gene Info
Gene SymbolTGFB2
Full NameTransforming Growth Factor Beta 2
Chromosome1q41
Functionis a member of the TGF-beta superfamily of cytokines that plays critical roles in neural development, synaptic plasticity, and neuroinflammation regulation[@massague2012][@krieglstein2012].
Molecular Weight47.7 kDa
Amino Acids414 aa
Exons7
PathwaysTGF-β
UniProt IDP08123
NCBI Gene ID7048
Ensembl IDENSG00000192958
OMIM190220
GeneCardsTGFB2
Human Protein AtlasTGFB2
Associated DiseasesCancer, Carcinoma, Ms, Tumor
InteractionsBMP7, BMP4, TGFBR1, AND
KG Connections31 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (2)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (14)

VEGFB Gene
gene · KG edge: expressed_in
TGFBR2 (Transforming Growth Factor Beta Receptor 2)
gene · KG edge: associated_with
TGFBR1 — TGF-beta Receptor 1
gene · KG edge: activates
TGFB1 — Transforming Growth Factor Beta 1
gene · KG edge: expressed_in
PDGFB — Platelet Derived Growth Factor Subunit B
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

TGFB2 activates BMP7
TGFB2 associated_with E2F5
TGFB2 associated_with CDKN2B
TGFB2 expressed_in VEGFB
TGFB2 expressed_in CSF2
TGFB2 expressed_in Vegf
TGFB2 expressed_in Rb
TGFB2 associated_with Carcinoma
TGFB2 associated_with Ms
TGFB2 associated_with Cancer