gene 815 words KG: CDK4
Contents

CDK4 Gene

🧬 Gene Info
Gene SymbolCDK4
Full NameCyclin-Dependent Kinase 4
Chromosome12q14.1
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight34 kDa
Amino Acids303 aa
Exons8
PathwaysAkt, Dna Methylation, Epigenetic, Pi3K
UniProt IDP11802
NCBI Gene ID1019
Ensembl IDENSG00000136492
GeneCardsCDK4
Human Protein AtlasCDK4
Associated DiseasesAls, Cancer, Carcinoma, glioblastoma, Melanoma
InteractionsACTB, AKT, AND, APOPTOSIS, ARAF, ATF4
KG Connections407 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (2)

p21^Cip1 Phospho-State as Autophagy Responsiveness Predictor
Score: 0.77
Dual BCL-2/CDK4/6 Inhibition for Enhanced Senolytic Efficacy
Score: 0.00

Knowledge Graph (12 edges)

RANK activates CDK4
RANKL activates CDK4
CDK4 associated_with CASP3
CDK4 regulates PI3K
CDK4 associated_with ESR1
CDK4 associated_with CHEK1
CDK4 associated_with MTOR
CDK4 associated_with PIK3CA
CDK4 associated_with GSK3B
CDK4 regulates AKT

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