gene 680 words KG: CREBBP 2026-03-22
kind:genesection:genesstate:published
Contents

CREBBP Gene

🧬 Gene Info
Gene SymbolCREBBP
Full NameCREB Binding Protein
Chromosome16p13.3
Protein TypeTranscription Factor
Functionis a transcriptional coactivator that acetylates histones and transcription factors
Primary Expressionmost neuronal subtypes including pyramidal cells, interneurons - Glia: Present in astrocytes and [microglia](/entities/mic
Molecular Weight265 kDa
PathwaysNF-ÎșB
UniProt IDQ92793 (CREBBP)
NCBI Gene ID1387
Ensembl IDENSG00000105383
OMIM600140
GeneCardsCREBBP
Human Protein AtlasCREBBP
Associated DiseasesALS, Cancer, Parkinson, Tumor
Known Drugs/Compoundsrapamycin
InteractionsIL6ST, CREB1, KMT2D, BCL2, LRP1, CALCOCO2
KG Connections491 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Knowledge Graph (12 edges)

CREBBP activates EP300
CREBBP activates FIP200
CREBBP activates GAPDH
CREBBP activates HDAC6
CREBBP activates HSP70
CREBBP activates HSPA8
CREBBP activates KAT2A
CREBBP activates KAT2B
CREBBP activates KAT5
CREBBP activates KAT8