gene 1,398 words KG: EIF4G1
Contents

EIF4G1 Gene

🧬 Gene Info
Gene SymbolEIF4G1
Chromosome3p14.2
Functionis a large scaffolding protein (approximately 175 kDa) that serves as the core component of the eIF4F translation initiation complex.
Molecular Weight220 kDa
Amino Acids1598 aa
Exons33
PathwaysNF-κB, mTOR
Ensembl IDENSG00000114867
GeneCardsEIF4G1
Human Protein AtlasEIF4G1
Associated Diseasesneurodegeneration
InteractionsATG5, ATP13A2, ATXN2, CASP1, CHMP3, DISC1
KG Connections51 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

CASP1 interacts_with EIF4G1
MAPK8 interacts_with EIF4G1
CD8 expressed_in EIF4G1
EIF4G1 interacts_with ATG5
ATXN2 activates EIF4G1
LRRK2 activates EIF4G1
ATP13A2 activates EIF4G1
VPS35 activates EIF4G1
NBN regulates EIF4G1
SGK3 regulates EIF4G1

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