gene 695 words KG: FOS
Contents

FOS Gene

🧬 Gene Info
Gene SymbolFOS
Full NameFBJ Murine Osteosarcoma Viral Oncogene Homolog
Chromosome14q24.3
Protein TypeTranscription Factor
FunctionFOS is an immediate-early gene encoding a leucine zipper transcription factor.
Molecular Weight40.6 kDa
PathwaysImmune Response, Neurogenesis, Nf-Kb, Nf-Κb, Synaptic Plasticity
UniProt IDP01100
NCBI Gene ID2353
Ensembl IDENSG00000170345
OMIM164810
GeneCardsFOS
Human Protein AtlasFOS
Activity-dependent transcriptionResponds to neuronal firing and calcium influx
AP-1 complex formationHeterodimers with JUN family proteins (c-JUN, JUNB, JUND)
Associated DiseasesAls, Alzheimer, Atherosclerosis, Cancer, Ischemia, Ms
Known Drugs/Compoundspokeweed mitogen
InteractionsActin, AKT1, ALZHEIMER, ALZHEIMER'S DISEASE, AND, ANXIETY
KG Connections486 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

FOS contributes_to AP1
pokeweed mitogen activates FOS
EGF activates FOS
PIEZO1 activates FOS
SRC activates FOS
EGFR activates FOS
JUN activates FOS
P38 activates FOS
FOS activates SRC
JUN interacts_with FOS

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