gene 842 words KG: GALC
Contents

GALC Gene

🧬 Gene Info
Gene SymbolGALC
Full NameGalactocerebrosidase
Chromosome14q31.3 (Chr14: 87,934,475-88,013,430)
FunctionGALC encodes galactocerebrosidase, a lysosomal hydrolase that catalyzes the hydrolysis of galactocerebroside, a major lipid component of myelin.
Primary Expressionbrain white matter, peripheral nerves
Molecular Weight80 kDa
PathwaysTgf-Β
UniProt IDP54803
NCBI Gene ID2581
Ensembl IDENSG00000135837
OMIM245000
GeneCardsGALC
Human Protein AtlasGALC
Associated DiseasesMs
InteractionsAUTOPHAGY, CANCER, CTSD, GLA, GPR37, LRRK2
KG Connections41 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

GALC activates RAC1
GALC interacts_with PSAP
GALC activates GPR37
GALC activates SMAD4
GALC interacts_with CTSD
ARSA associated_with GALC
GLA associated_with GALC
GALC contributes_to PSAP
GFAP causes GALC
GALC causes PLP1

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