gene 2,729 words KG: RAC1 2026-03-28
kind:genesection:genesstate:published
Contents

RAC1 Gene

🧬 Gene Info
Gene SymbolRAC1
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight21.4 kDa
Amino Acids192 aa
PathwaysApoptosis, Autophagy, Dendritic Spine, Mtor, Nf-Κb
Ensembl IDENSG00000136238
GeneCardsRAC1
Human Protein AtlasRAC1
Associated DiseasesALS, Cancer, Diabetes, Encephalitis, Inflammation
InteractionsSTAT3, PAK1, ATG12, TFEB, ELP3, ATG5
KG Connections491 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (23)

Astrocytic Connexin-43 Upregulation Enhances Neuroprotective
Score: 0.45
CYP46A1 Overexpression Gene Therapy
Score: 0.63
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.57
Phase-Separated Organelle Targeting
Score: 0.52
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.52

Related Analyses (12)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed

See Also (12)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: regulates
Alzheimer Indonesia
institution · KG edge: activates
APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: inhibits
ASC (PYCARD)
gene · KG edge: associated_with
ARHGEF7 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

RAC1 associated_with PIK3C3
RAC1 regulates ATG14
RAC1 regulates GJA1
RAC1 associated_with LAMP1
RAC1 therapeutic_target MET
RAC1 therapeutic_target MMP9
RAC1 therapeutic_target VIM
RAC1 regulates TPM2
RAC1 therapeutic_target NCF1
RAC1 regulates BECN1