gene 2,729 words KG: RAC1
Contents

RAC1 Gene

🧬 Gene Info
Gene SymbolRAC1
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight21.4 kDa
Amino Acids192 aa
PathwaysApoptosis, Autophagy, Dendritic Spine, Mtor, Nf-Κb
Ensembl IDENSG00000136238
GeneCardsRAC1
Human Protein AtlasRAC1
Associated DiseasesAls, Cancer, Diabetes, Encephalitis, Inflammation
InteractionsACTB, Actin, ACVR1, AKT, AKT1, ALZHEIMER
KG Connections483 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (23)

Astrocytic Connexin-43 Upregulation Enhances Neuroprotective
Score: 0.68
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.83
CYP46A1 Overexpression Gene Therapy
Score: 0.77
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
Phase-Separated Organelle Targeting
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72
Microglial Efferocytosis Enhancement via GPR32 Superagonists
Score: 0.70
Purinergic P2Y12 Inverse Agonist Therapy
Score: 0.70
Microglial Purinergic Reprogramming
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Reelin-Mediated Cytoskeletal Stabilization Protocol
Score: 0.69
Lysosomal Positioning Dynamics Modulation
Score: 0.69
Oligodendrocyte Protectin D1 Mimetic for Myelin Resolution
Score: 0.68
Complement C1q Subtype Switching
Score: 0.66
RNA Granule Nucleation Site Modulation
Score: 0.66
Ephrin-B2/EphB4 Axis Manipulation
Score: 0.64
Quantum Coherence Disruption in Cellular Communication
Score: 0.63
Synaptic Phosphatidylserine Masking via Annexin A1 Mimetics
Score: 0.62
TREM2-mediated microglial tau clearance enhancement
Score: 0.62
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Related Analyses (12)

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

See Also (12)

Apoptosis in Neurodegeneration
entity · KG edge: regulates
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: activates
ACTB Gene
gene · KG edge: regulates
ACVR1 Gene
gene · KG edge: interacts_with
AKT1 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

VAV1 activates RAC1
ACTB regulates RAC1
CDC42 regulates RAC1
CASP3 regulates RAC1
SQSTM1 associated_with RAC1
TUBB3 associated_with RAC1
STK11 associated_with RAC1
VIM associated_with RAC1
BECN1 regulates RAC1
HDAC6 associated_with RAC1

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