| Gene Symbol | PPARA |
| Chromosome | 22q13.31 |
| Protein Type | Transcription Factor |
| Function | encodes a ligand-activated transcription factor belonging to the nuclear receptor superfamily. |
| Primary Expression | tissues with high fatty acid catabolism, including liver, heart, skeletal muscle, and kidney |
| Amino Acids | 468 aa |
| Exons | 8 |
| Pathways | Akt, Autophagy, Mapk, Mtor, Sphingolipid |
| Ensembl ID | ENSG00000186951 |
| GeneCards | PPARA |
| Human Protein Atlas | PPARA |
| Associated Diseases | AD, ADH, Als, Alzheimer disease, Alzheimer's disease, AMI |
| Known Drugs/Compounds | Bezafibrate, gemfibrozil, rapamycin, Wy14643 |
| Interactions | ACACA, ACOX1, Adiponectin, ADIPOQ, AKT1, ALDH2 |
| SciDEX Hypotheses | Cell-Type Specific Metabolic Reprogramming Palmitoylethanolamide-Based Endocannabinoid Therap |
| KG Connections | 539 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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