| Gene Symbol | APOB |
| Full Name | Apolipoprotein B |
| Chromosome | Chr2p24.1 |
| Function | The APOB gene encodes Apolipoprotein B, the main structural protein of very-low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) particles. |
| Pathways | Cholesterol, Dna Methylation, Wnt |
| UniProt ID | P04114 |
| NCBI Gene ID | 338 |
| Ensembl ID | ENSG00000184677 |
| OMIM | 107730 |
| GeneCards | APOB |
| Human Protein Atlas | APOB |
| APOB-100 | Full-length protein synthesized in liver, found on VLDL/LDL |
| APOB-48 | Truncated form from intestinal mRNA, found on chylomicrons |
| N-terminal region | Lipid-binding beta-sheet structure (LDLR binding) |
| Central region | Large beta-sheet domains |
| Associated Diseases | AD, ADH, ALI, Als, AMI, cancer |
| Interactions | CANCER, DNA, EEF1A1, GENES, IDH1, JUN |
| KG Connections | 149 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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