gene 746 words KG: ARHGEF2 2026-03-27
kind:genesection:genesstate:published
Contents

ARHGEF2 Gene

🧬 Gene Info
Gene SymbolARHGEF2
Full NameRho Guanine Nucleotide Exchange Factor 2
Chromosome1q22
FunctionARHGEF2 encodes a Rho GEF that activates Rho GTPases, primarily RhoA, but also Rac1 and Cdc42.
Molecular Weight220 kDa
Amino Acids736 aa
Exons33
UniProt IDQ9Y5S5
NCBI Gene ID9199
Ensembl IDENSG00000116584
OMIM607560
GeneCardsARHGEF2
Human Protein AtlasARHGEF2
Gene NameRho Guanine Nucleotide Exchange Factor 2 (LARG)
Associated DiseasesIntellectual disability, Midbrain-hindbrain malformation
InteractionsRhoA, Rac1, CaMKK2, SQSTM1, TPM3, NPM1
KG Connections38 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph